Excessive exposure to manganese can lead to its accumulation in the body and damage to the nervous system. The best-documented cases of poisoning relate to chronic inhalation of dust or fumes containing manganese, including during welding and mining. Exposure linked to drinking water with very high concentrations of this element has also been reported. Cases of poisoning resulting from the consumption of a typical, varied diet are not well documented. In its 2023 assessment, the EFSA identified 8 mg per day as the intake level considered safe for adults, including manganese from food, water and supplements.
Symptoms of long-term excessive exposure may include impaired concentration and memory, mood swings, irritability, slowness of movement, tremors, muscle stiffness, and problems with walking and balance. In advanced cases, movement disorders resembling Parkinson’s disease may occur, although they have a different aetiology. People with chronic liver disease are particularly at risk of manganese accumulation. Iron deficiency may further increase its absorption.
Manganese is essential for the body’s energy metabolism, maintaining healthy bones and protecting cells from oxidative stress. Good sources of manganese include whole grains, nuts, seeds and pulses. Manganese deficiency is very rare; therefore, with a varied diet, there is usually no need for additional supplementation.
FAQ – frequently asked questions about manganese
What does manganese do and what role does it play in the body?
Manganese plays a part in nutrient metabolism, helps maintain healthy bones and supports the proper formation of connective tissue. It is also a component of an enzyme that helps protect cells from oxidative stress.
Which foods are richest in manganese?
Good sources of manganese include nuts, seeds, whole grains and pulses. Macadamia nuts, pine nuts, hazelnuts and chia seeds are particularly rich in manganese. Manganese is also found in porridge, brown rice and tea.
How much manganese does a person need each day?
According to the EFSA, the adequate intake of manganese for adults is 3 mg per day. This is a guideline level, not a daily supplement dose.
What are the symptoms of manganese deficiency?
Manganese deficiency is very rare and there are no clear-cut symptoms to identify it. Limited studies have described skin changes, hair pigmentation disorders and metabolic abnormalities, but these symptoms are not specific to manganese deficiency alone.
Can a manganese deficiency cause bone problems?
Manganese plays a role in processes related to maintaining healthy bones and the formation of connective tissue. However, this does not mean that bone or joint pain is a sign of a manganese deficiency. Such symptoms can have many other causes.
Is it possible to overdose on manganese from food?
An overdose of manganese is unlikely when following a normal, varied diet. Greater risks may arise from excessive occupational exposure, contaminated drinking water or the unnecessary intake of manganese-containing supplements.
What is a safe amount of manganese?
In its 2023 assessment, the EFSA identified 8 mg per day as the intake level considered safe for adults. This refers to the total amount of manganese from food, water and supplements, rather than a recommended daily dose.
Are manganese and magnesium the same element?
No. Manganese and magnesium are two different minerals. Manganese is a trace element required in small amounts, whilst magnesium is a macromineral of which the body needs significantly more.
Who should be particularly careful about excess manganese?
People with chronic liver disease should exercise greater caution, as they may have difficulty eliminating excess manganese. Iron deficiency is also a factor, as it can increase the absorption of this element. In such situations, manganese supplements should not be taken without consulting a specialist.
Sources:
- Erikson, K. M., & Aschner, M. (2019). Manganese: Its Role in Disease and Health. Metal ions in life sciences, 19, /books/9783110527872/9783110527872-016/9783110527872-016.xml. https://doi.org/10.1515/9783110527872-016
- Kippler, M., & Oskarsson, A. (2024). Manganese - a scoping review for Nordic Nutrition Recommendations 2023. Food & nutrition research, 68, 10.29219/fnr.v68.10367. https://doi.org/10.29219/fnr.v68.10367
- Magro, G., Laterza, V., Tosto, F., & Torrente, A. (2025). Manganese Neurotoxicity: A Comprehensive Review of Pathophysiology and Inherited and Acquired Disorders. Journal of xenobiotics, 15(2), 54. https://doi.org/10.3390/jox15020054